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Epub Jul The Fas receptor CD95 mediates apoptotic signaling by Fas- ligand expressed on the surface of other cells.

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Analogs were tested with different chemotypes. It also has been suggested that GSK-3 promotes activation and translocation of the proapoptotic Bc family member, Bax, which, upon agregation and mitochondrial localization, induces cytochrome c release. The terms "therapeutic agent" and "active agent" are used interchangeably herein.

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Another apoptosis activated protease is endonuclease G EndoG.:

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